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Learning Clubs and Series Platelets mediate the clearance of senescent red blood cells by forming pro-phagocytic platelet-cell complexes

Platelets mediate the clearance of senescent red blood cells by forming pro-phagocytic platelet-cell complexes

Short name: AJCJ242024
Course start date: 07/11/2025
Course end date: 07/11/2026

Description

ASH Journal Club: January 24, 2024, 3:00-4:00 PM Eastern 

The ASH Journal Club is a series that highlights seminal papers in hematology published in Blood, Blood AdvancesBlood Neoplasia, and Blood Vessels, Thrombosis, & Hemostasis and features a manuscript author as part of the engagement. Join us on January 24th, 2024 to discuss “Platelets mediate the clearance of senescent red blood cells by forming pro-phagocytic platelet-cell complexes,” Blood (2023). Published to First Edition on November 22, 2023. DOI: https://doi.org/10.1182/blood.2023021611.  

Learning Objectives

Come learn about how senescent red blood cells (RBC) are bound to platelets, forming platelet-RBC complexes which are selectively consumed by erythrophagocytes and how a sufficient supply of platelets is required to maintain efficient complex-dependent clearance of senescent RBC.

Presenter:

 

Brendan McMorran, PhD
Australian National University


Moderators:

   

Elisabeth Battinelli, MD, PhD 
Brigham and Women’s Hospital

 

Kellie Machlus, PhD
Boston Children’s Hospital


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ASH Journal Club: January 24, 2024, 3:00-4:00 PM E...
Platelets mediate the clearance of senescent red blood cells by forming pro-phagocytic platelet-cell complexes
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Price
Free Access
Duration
30-60 minutes
Accreditation
Not Accredited
Frequently Searched Content
Image Challenges
Research
  • Basic Science
  • Pre-Clinical Models
  • Translational
Learning Level
Level 3/Subspecialty: Fellows developing general hematology expertise for board certification
Disease Types and Treatments
  • Platelet disorders
  • Red cell disorders
Platelet disorders
  • Normal platelet and megakaryocyte physiology
Red Cell Disorders
  • Normal red cell physiology

Tag

Normal platelet and megakaryocyte physiology Normal red cell physiology Platelet disorders Red cell disorders Research - Basic Science Research - Pre-Clinical Models Research - Translational