Enhanced tyrosine kinase inhibitor response on chronic myeloid leukemia cells upon MS4A3 mRNA delivery
1 activities
Enhanced tyrosine kinase inhibitor response on chronic myeloid leukemia cells upon MS4A3 mRNA delivery
CD19 antigen From tumor target to safety switch able to improve the safety profile of CAR T cell therapy
1 activities
CD19 antigen From tumor target to safety switch able to improve the safety profile of CAR T cell therapy
Long term follow up of the first in human post transcriptional genetic silencing of BCL11A in sickle cell disease in a phase 1 pilot and feasibility trial
1 activities
Long term follow up of the first in human post transcriptional genetic silencing of BCL11A in sickle cell disease in a phase 1 pilot and feasibility trial
Robust HbF induction and improvement of anemia and hemolysis with base editing in sickle cell disease Safety and efficacy findings from the ongoing BEACON study
1 activities
Robust HbF induction and improvement of anemia and hemolysis with base editing in sickle cell disease Safety and efficacy findings from the ongoing BEACON study
Multiplex base editing enhances fetal hemoglobin production in sickle cell disease erythroid cells
1 activities
Multiplex base editing enhances fetal hemoglobin production in sickle cell disease erythroid cells
Targeting the METTL1 m7G axis as a therapeutic strategy in myeloid leukemia
1 activities
Targeting the METTL1 m7G axis as a therapeutic strategy in myeloid leukemia
MiR 146b restoration in T large granular lymphocyte leukemia Molecular insights for a new therapeutic strategy
1 activities
MiR 146b restoration in T large granular lymphocyte leukemia Molecular insights for a new therapeutic strategy
Prime Editing–Mediated BCL 2 hematopoietic stem cell shielding as a strategy for leukemia therapy
1 activities
Prime Editing–Mediated BCL 2 hematopoietic stem cell shielding as a strategy for leukemia therapy