621. Lymphomas: Translational Molecular and Genetic: Poster I

Pharmacologic overactivation of ALK activity by PTPN2 PTPN1 inhibition induces a combination of tumor intrinsic oncogenic stress and immune responses to promote tumor eradication in ALK positive lymphoma

NOTCH pathway activation is mediated by DTX1 loss of function mutations in DLBCL

B like natural killer cells related to the epstein barr virus infection present an adaptive immune phenotype and stronger killing activity in lymphomas

Enrichment of rare pathogenic variants in common cancer predisposition genes in lymphatic malignancy A comprehensive analysis of 2 138 cases

MSK impact heme accurately reproduces diffuse large B cell DLBCL dlbclass cluster classification across clinical scenarios including diagnosis relapse and histological transformation

Pre treatment circulating tumor DNA predicts survival of diffuse large B cell lymphoma patients and allows genetic and biological evaluation

Single cell and spatial transcriptomics analyses decipher malignant B cell heterogeneity and immunosuppressive microenvironment in primary central nervous system lymphoma

Genomic and transcriptomic landscape of extranodal marginal zone lymphoma

Clinical characteristics and whole exome sequencing based genomic profiling of post transplant lymphoproliferative disorders following allogeneic hematopoietic stem cell transplantation

Prognostic impact of cytogenetic abnormalities in aggressive T cell lymphomas Defining high risk subgroups through conventional karyotyping

Integrated multi omic profiling identifies molecular subtypes and predicts outcomes in newly diagnosed peripheral T cell lymphomas

Generation of faithful autochthonous mouse models of Mantle Cell Lymphoma

B and T cell clonality using peripheral blood cell free RNA cfRNA in liquid biopsy

Multiparametric integration improves diagnostic categorisation of mature non CLL B cell leukemias including atypical CLL results from the prospective enable NGS study

Assessment of EBV DNA methlyation to guide antiviral use in EBV associated lymphoma

Multi dimensional transcriptomic profiling reveals novel tumor microenvironment landscape and subtype specific therapeutic Vulnerabilities of MALT lymphomas

Impact of PRF 1 A91V germline carrier status in patients with aggressive b NHL treated with rituximab

Identifying biological differences between two clinical risk groups of cutaneous CD30 T cell lymphoproliferative disorders

Non invasive detection and classification of lymphoma via cell free DNA methylation profiling