603. Lymphoid Oncogenesis: Basic: Poster III

Identification of NAE1 dependent β catenin neddylation as selective vulnerability in B cell malignancies

The NLP protein is a novel regulator of G2 m Phase of the cell cycle critical for proliferation of human peripheral T cell lymphomas

RNA−binding protein FXR1 stabilizes receptor tyrosine kinase FGFR1 and enhances PI3K−Akt signaling to promote T−cell leukemogenesis

CELF2 deficient mutations promote B cell lymphoma development by inducing a germinal center B cell fate

TP53 mutation promotes diffuse large B cell lymphoma progression via mediating lactylation of ATP5E at Lys44

IL 17–Induced CD70 expression promotes T cell suppression in DLBCL Implications for immune escape and T cell exhaustion

Functional analysis of STAT3 activating mutations in LGL leukemia reveals epigenetic reprograming and therapeutic vulnerabilities

PARP1 facilitates transcriptional activity and stability of the BCL6 protein and is a therapeutic target in BCL6 expressing lymphomas

Single cell analysis and functional profiling reveal galectin 3–driven reprogramming of the tumor immune microenvironment in transformed follicular lymphoma

Chromatin remodeler SATB2 thorough Bmi1 PRC1 activity controls transformation and reprogramming of ph B cell progenitors

Cutaneous diffuse large B cell lymphoma induce a macrophage immunosuppressive phenotype through IL 10 secretion