602. Myeloid Oncogenesis: Basic: Poster I

Single cell tracing of myeloid leukemia evolution in down syndrome reveals a latent progenitor bridging disease onset progression and relapse

ENO1 promotes Acute Myeloid Leukemia progression through SCD1 mediated lipid metabolism reprogramming

Cd39 overexpression in AML blasts elicits an immune suppressive bone barrow microenvironment via G3 G4 neutrophils and Th1 cells

Missense mutations in the PWWP domain of DNMT3A can cause cytoplasmic mislocalization of DNMT3A in AML cells

The chromatin remodeling protein ARID1A is required for MLL AF9 leukemogenesis

Azin1 tecr reprograms fatty acid metabolism to drive Acute Myeloid Leukemia progression

Synergistic effects of ASXL1 and BCOR on hematopoiesis and MDS AML progression

Acute depletion of HOXA9 reveals its direct role in cis elements regulation and 3D genome organization during Acute Myeloid Leukemia

ST2 promotes leukemia transformation by reshaping the immune landscape in Acute Myeloid Leukemia

Clonal heterogeneity of acute myeloid leukemia under nutrient and chemotherapy stress

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Allergin 1 marks leukemic stem cells and enables immune evasion in AML A target for therapeutic antibody development

Inhibition of prolyl tRNA synthetase sensitizes acute myeloid leukemia to venetoclax through bmf mediated apoptosis

The PDI ATF6 axis as a novel treatment target in CSF3R driven chronic neutrophilic leukemia CNL

Ribosome biogenesis and its regulation by the exportin CSE1L are targetable vulnerabilities in childhood and young adult Acute Myeloid Leukemia

Repertoire of driver events in coding and non coding regions identified by whole genome sequencing of myeloid neoplasms

The role of G0S2 in FLT3 AML bone marrow microenvironment and metabolism