704. Cellular Immunotherapies: Early Phase Clinical Trials and Toxicities: Poster III
0 activities
High complete response rates, low dropout rate, and low-grade toxicities in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) receiving GLPG5101, a fresh, early memory-enriched CAR T-cell therapy with a 7-day vein-to-vein time
1 activities
High complete response rates, low dropout rate, and low-grade toxicities in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) receiving GLPG5101, a fresh, early memory-enriched CAR T-cell therapy with a 7-day vein-to-v
Prophylactic dexamethasone to reduce risk of cilta cel associated immune effector cell delayed neurotoxicity
1 activities
Prophylactic dexamethasone to reduce risk of cilta cel associated immune effector cell delayed neurotoxicity
Increased alemtuzumab exposure correlates with improved responses in heavily pretreated R R ALL patients Analysis of the balli 01 trial
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Increased alemtuzumab exposure correlates with improved responses in heavily pretreated R R ALL patients Analysis of the balli 01 trial
Administration of off the shelf expanded most closely HLA matched third party viral specific T cells for the therapy of adenovirus related disease in adult immunocompromised patients
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Administration of off the shelf expanded most closely HLA matched third party viral specific T cells for the therapy of adenovirus related disease in adult immunocompromised patients
First in human Phase I study of autologous CD5 knockout anti CD5 CAR T cells in CD5 hematologic malignancies
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First in human Phase I study of autologous CD5 knockout anti CD5 CAR T cells in CD5 hematologic malignancies
Unveiling the second wave Viral triggered biphasic CAR T expansion drives late onset IEC HS Characterization and successful management
1 activities
Unveiling the second wave Viral triggered biphasic CAR T expansion drives late onset IEC HS Characterization and successful management
Point of care anti CD19 CAR T for autoimmune diseases
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Point of care anti CD19 CAR T for autoimmune diseases
CCR5 blockade A therapeutic approach to uncouple CART BCMA expansion from CART mediated immune toxicities
1 activities
CCR5 blockade A therapeutic approach to uncouple CART BCMA expansion from CART mediated immune toxicities
MT 601 demonstrates favorable safety and durable responses in relapsed or refractory r r non Hodgkin lymphoma NHL
1 activities
MT 601 demonstrates favorable safety and durable responses in relapsed or refractory r r non Hodgkin lymphoma NHL
Defining a high risk population for CAR T cell therapy The impact of clonal hematopoiesis and pre existing neutropenia on severe outcomes in patients treated for malignant and non malignant conditions
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Defining a high risk population for CAR T cell therapy The impact of clonal hematopoiesis and pre existing neutropenia on severe outcomes in patients treated for malignant and non malignant conditions
Donor derived secondary CAR T cell therapy for relapsed leukemia following initial CAR T bridged to allogeneic transplantation Efficacy and safety analysis
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Donor derived secondary CAR T cell therapy for relapsed leukemia following initial CAR T bridged to allogeneic transplantation Efficacy and safety analysis
Donor derived CAR T cells co infused with the allogenic graft on the platform of T cell depletion or post transplant cyclophosphamide in children with advanced B cell neoplasms
1 activities
Donor derived CAR T cells co infused with the allogenic graft on the platform of T cell depletion or post transplant cyclophosphamide in children with advanced B cell neoplasms
Long term follow up autologous CD30 CAR T cells in combination with nivolumab in patients with relapsed or refractory classical Hodgkin lymphoma after failure of frontline therapy
1 activities
Long term follow up autologous CD30 CAR T cells in combination with nivolumab in patients with relapsed or refractory classical Hodgkin lymphoma after failure of frontline therapy
Torque teno virus in pediatric CAR T recipients
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Torque teno virus in pediatric CAR T recipients
Safety and efficacy of less differentiated CAR T cell products in relapsed refractory B cell non Hodgkin lymphomas A meta analysis
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Safety and efficacy of less differentiated CAR T cell products in relapsed refractory B cell non Hodgkin lymphomas A meta analysis
Lipo MIT based bridging therapy enables effective CAR T treatment in high risk relapsed or refractory B cell lymphoma
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Lipo MIT based bridging therapy enables effective CAR T treatment in high risk relapsed or refractory B cell lymphoma
A tandem bispecific nanobody CAR SL1703 T cells targeting CD19 BCMA for refractory or relapsed multiple myeloma as salvage treatment after BCMA CAR T therapy failure
1 activities
A tandem bispecific nanobody CAR SL1703 T cells targeting CD19 BCMA for refractory or relapsed multiple myeloma as salvage treatment after BCMA CAR T therapy failure
Novel bispecific epitope anti CD5 nanobody CAR T cells for refractory or relapsed T cell malignancies
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Novel bispecific epitope anti CD5 nanobody CAR T cells for refractory or relapsed T cell malignancies
Impact of clonal hematopoiesis on hematologic recovery and outcomes following tumor infiltrating lymphocyte therapy
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Impact of clonal hematopoiesis on hematologic recovery and outcomes following tumor infiltrating lymphocyte therapy
Long term remission and survival in patients with relapsed or refractory non Hodgkin lymphoma after treatment of brl 201 a CRISPR based non viral PD 1 locus specifically integrated anti CD19 CAR T cells 4 year follow up of a first in human phase I study
1 activities
Long term remission and survival in patients with relapsed or refractory non Hodgkin lymphoma after treatment of brl 201 a CRISPR based non viral PD 1 locus specifically integrated anti CD19 CAR T cells 4 year follow up of a first in human
Autologous hematopoietic stem cell transplantation combined with inaticabtagene autoleucel in adults with high risk B cell acute lymphoblastic leukemia Interim analysis of a phase II study
1 activities
Autologous hematopoietic stem cell transplantation combined with inaticabtagene autoleucel in adults with high risk B cell acute lymphoblastic leukemia Interim analysis of a phase II study
Impact and predictors of icans on survival in lymphoma and myeloma patients treated with CAR T cell therapy
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Impact and predictors of icans on survival in lymphoma and myeloma patients treated with CAR T cell therapy
Allogeneic induced pluripotent stem cell derived invariant natural killer T cell therapy A phase 1 clinical Trial
1 activities
Allogeneic induced pluripotent stem cell derived invariant natural killer T cell therapy A phase 1 clinical Trial
Unsupervised proteomic and metabolomic longitudinal serum profiling of anti CD19 CAR T cell therapy recipients reveals clinically distinct groups
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Unsupervised proteomic and metabolomic longitudinal serum profiling of anti CD19 CAR T cell therapy recipients reveals clinically distinct groups
Phase 1 clinical trial of point of care manufactured fully human anti CD19 CAR T cells for treatment of Relapsed Refractory lymphoid malignancies
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Phase 1 clinical trial of point of care manufactured fully human anti CD19 CAR T cells for treatment of Relapsed Refractory lymphoid malignancies
Autologous hematopoietic stem cell transplantation followed by CD19 CD22 dual target CAR T therapy for refractory or relapsed burkitt lymphoma
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Autologous hematopoietic stem cell transplantation followed by CD19 CD22 dual target CAR T therapy for refractory or relapsed burkitt lymphoma
Glofitamab for patients with Non–Large B cell lymphoma refractory or relapsing after anti CD19 CAR T cell therapy Final bicar study LYSA results
1 activities
Glofitamab for patients with Non–Large B cell lymphoma refractory or relapsing after anti CD19 CAR T cell therapy Final bicar study LYSA results