508. Bone Marrow Failure: Acquired: Poster II

Complete donor chimerism following deceased donor liver transplant in an adolescent with hepatitis associated severe aplastic anemia

Clonal hematopoiesis and immune dysregulation in classic PNH

Global immunopeptidome remodeling favors piga mutant clones in bone marrow failure

Disrupted DNA repair and oxidative stress responses underlie hematopoietic stem cell failure after spinal cord injury

Iptacopan monotherapy demonstrated improved clinical outcomes in a real world cohort with paroxysmal nocturnal hemoglobinuria Evidence from a managed access program

Outcomes of eltrombopag combined with immunosuppressive therapy in adults with severe aplastic anemia A large propensity matched retrospective analysis

Sodium glucose cotransporter 2 inhibitors may modulate complement pathway activation in paroxysmal nocturnal hemoglobinuria

Maternal and fetal pharmacokinetics PK of pegcetacoplan in paroxysmal nocturnal hemoglobinuria PNH A case report of use in pregnancy

Long term safety and efficacy of iptacopan in patients with paroxysmal nocturnal hemoglobinuria 4 and 5 year follow up of patients from Phase 2 studies who entered the roll over extension program

Long term follow up of patients with aplastic anemia enrolled in two phase 2 3 trials of immunosuppressive therapy plus romiplostim as a first line treatment Final report for up to 5 years

Efficacy and safety of romiplostim N01 combined with cyclosporine in refractory aplastic anemia patients a multicenter phase II study

The effect of breakthrough hemolysis on complement factor h and factor I levels in paroxysmal nocturnal hemoglobinuria

Thymoglobuline and grafalon show comparable transplant outcomes in patients with aplastic anemia undergoing allogeneic stem cell transplantation A multicenter EBMT saawp study of 1603 patients

Comprehensive multiproteomic analysis reveals an inflammatory phenotype in immune aplastic anemia characterized by broad activation of antigen presenting cells and t helper cytotoxic 1 17 immune responses

Early results from the ongoing pegcetacoplan silo of the international paroxysmal nocturnal hemoglobinuria interest group registry

Treatment requiring paroxysmal nocturnal hemoglobinuria in association with myeloproliferative neoplasms MPNs Clinical correlations and outcomes