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Conferences and Meetings 113. Sickle Cell Disease, Sickle Cell Trait, and Other Hemoglobinopathies, Excluding Thalassemias: Basic and Translational: Poster III

113. Sickle Cell Disease, Sickle Cell Trait, and Other Hemoglobinopathies, Excluding Thalassemias: Basic and Translational: Poster III

Short name: updated-113. Sickle Cell Disease, Sickle Cell Trait, and Other Hemoglobinopathies, Excluding Thalassemias: Basic and Translational: Poster III-2025 Annual Meeting Poster Bundle Erythroid Development & Iron Metabolism
Course start date: 02/04/2026

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Circulating endothelial extracellular vesicles from sickle cell patients promote susceptibility of pulmonary endothelium to thrombotic injury
Sickling kinetics drive genotype specific impairment of RBC deformability in sickle cell disease
IHP 102 reduces pain and modulates complement activation in a sickle cell mouse model
IHP 102 compound decreases the adhesion of sickle cell disease RBCs to acutely activated endothelial cells in biochip labs endothelial on a chip assay
Mechanisms of acute pain involve spinal IL17 TNF α IL 6–p38 MAPK activation in sickle cell disease
Machine Learning–Guided identification of survival associated genetic variants in sickle cell disease
Impact of G6PD Α mutation on hemoglobin function and RBC rheology in sickle cell disease
Caspase 4 11 alters circulating immune cells and mediates organ damage in Townes SCD mice
Defining therapeutic chimerism thresholds for comprehensive sickle cell disease correction in the townes mouse model

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